Onion

Description

Medicinal Parts

The medicinal part is the bulb.

Flower and Fruit

The peduncles are up to 3 cm long. The flowers are greenish-white, in orbicular umbels, with 6 free flower bracts that are shorter than the 6 stamens. The pedicles are eight times as long as the flowers. The fruit is a thin-skinned capsule. The seeds are black and angular.

The flowers are in globular umbels, before blooming in membranous sheaths.

Leaves, Stem, and Root

The plant is perennial or biennial. There are many varieties and can be compressed-globose, ovate, or oblong. Most varieties have secondary bulbs. Leaves are shorter than the peduncle, tubular or swollen, and blue-green. There is a hollow scape, which is gray-blue, expanded, and bloated below the middle.

Habitat

Central Asia is considered to be the region of origin. Onion was introduced to the Mediterranean and is cultivated worldwide.

Production

Onion consists of the fresh or dried, thick and fleshy leaf sheaths and stipules of Allium cepa.

Actions & Pharmacology

Compounds

Alliins (alkylcysteine sulphoxides): in particular allylalliin (allyl-L-(+)-cysteine sulphoxide) and its gamma-glutamyl conjugates, that in the course of cutting up either the freshly harvested bulbs or those that have been already dried and then re-moistened, are transformed into the so-called alliaceous oils.

Fructosans (polysaccharides, 10-40%)

Saccharose and other sugars

Flavonoids: including quercetin-4′-O-beta-D-glucoside (spiraeoside)

Steroid Saponins

Effects

The thiosulphinate exhibits an antimicrobial effect, and is effective against Bacillus subtilis, Salmonella typhi, Pseudomonas aeroginosa and Escherichia coli.

Lipid and blood pressure-lowering effect

Certain constituents function similarly to those in garlic, although this is not yet clinically proven.

Inhibits thrombocyte aggregation

Dimethyl and diphenylthiosulphinateboth retard thrombocyte biosynthesis using thrombase stimulation.

Antiasthmatic and antiallergic effect

Guinea pigs sensitized using ovalbumin were protected from asthma attack through the oral administration of onion juice. Administration of an ethanol onion extract significantly reduced allergy-induced bronchial constriction in asthma patients.

Indications & Usage

Approved by Commission E:

  • Loss of appetite
  • Arteriosclerosis
  • Dyspeptic complaints
  • Fevers and colds
  • Cough/bronchitis
  • Hypertension
  • Tendency to infection
  • Inflammation of the mouth and pharynx
  • Common cold

Unproven Uses

In folk medicine, the drug is administered internally for whooping cough, asthma, tonsillitis, and angina. Onion has been used to stimulate gallbladder functions, for digestive disorders with bloating, flatulence, and colic pain, for dehydration, as an aid at the introduction of menstruation. Onion is also used for ascariasis, high blood pressure, arteriosclerosis and in the treatment of diabetes. Externally the drug is used for insect bites, wounds, light burns, furuncles, warts, and in the after-care of bruises.

Indian Medicine

Onion preparations are used for dyspeptic conditions, respiratory conditions, wounds, pain, and for malarial fever.

Chinese Medicine

Preparations are used for worm infestation, fungal, and bacterial infections.

Homeopathic Uses

Allium cepa is used for acute inflammatory illnesses, pain syndrome, and flatulent colic.

Precautions & Adverse Reactions

No health hazards or side effects are known in conjunction with the proper administration of designated therapeutic dosages. The intake of large quantities can lead to stomach complaints. Frequent contact with the drug leads on rare occasion to allergic reactions (hand eczema).

Dosage

Mode of Administration

Cut onions, pressed juice from fresh onions and other oral galenic preparations.

Preparation

Onion oil maceration: same as garlic maceration drug extract 1:1.

Old recipe: Siripus Cepae: freshly grated onions 15 g; water 60 ml; ethanol 90% (V/V) 15 mL; saccharose 150 g; the ethanolic extract is boiled with the saccharose.

Popular: pressed juice and onion syrup: made of 500 g onions, 500 g water, 100 g honey, and 350 g sugar.

Onion tincture: 100 g minced onions in 300 g ethanol 70% macerated for 10 days.

Daily Dosage

Raw drug is used therapeutically.

Externally the juice is spread or laid on as a poultice or in slices.

Internally: onion tincture 4 to 5 teaspoonfuls daily; onion syrup 4 to 5 tablespoons daily.

Average daily dose: 50 g of fresh onions or 20 g of dried drug.

Homeopathic Dosage

5 drops, 1 tablet, 10 globules every 30 to 60 minutes (acute) or 1 to 3 times daily (chronic); Parenterally: 1 to 2 mL 3 times daily sc; Ointment 1 to 2 times daily (HAB1)

Literature

Agarwal RH, Controlled trial of the effect of cycloalliin on the fibrinolytic activity of venous blood. In: Atherosclerosis 27:347-351. 1977.Ahluwalia P, Mohindroo A. Effect of Oral Ingestion of Different Fractions of Allium cepa on the Blood and Erythrocyte Membrane Lipids and Certain Membran-Bound Enzymes in Rats. J Nutr Sci Vitaminol. 35; 155-161. 1989Atta-Ur-Rahman Zaman K. Medicinal Plants with Hypoglycemic Activity. J Ethnopharmacol. 26; 1-55. 1989Bayer T, Breu W, Seligmann O, Wray V, Wagner H. Biologically active Thiosulphinates and alpha-Sulphinyl-Disulphides from Allium cepa. Phytochemistry 28; 2373-2377. 1989Bayer T, Wagner H, Wray V, Dorsch W. Inhibitors of Cyclo-Oxygenase and Lipoxygenase in Onions. Lancet II; 906. 1988Breu W. Allium cepa L. (Onion) / Part 1: Chemistry and analysis. Phytomedicine 3 (3); 293-306. 1996Breu W, Sendl A, Bürgi C, Rüedi P, Wagner H. In Vitro Inhibition of 5-Lipoxygenase by Extracts and Constituents of Plectranthus albidus and Allium ssp. Planta Med. 56; A665-A666. 1990Didry N, Dubreuil L, Pinkas M. Antimicobial Activity of Naphthoquinones and Allium Extracts Combined with Antibiotics. Pharm Acta Helv. 67; 148-151. 1992Dorsch W, Schnneider E, Bayer T, Breu W, Wagner H. Anti-Inflammatory Effects of Onions: Inhibition of Chemotaxis of Human Polymorphonuclear Leukocytes by Thiosulfinates and Cepaenes. Int Arch Allergy Appl Immunol. 92; 39-42. 199)Ernst E. Plants with hypoglycemic activity in humans. Phytomedicine 4 (1); 73-78. 1997Fossen T, Pedersen AT, Andersen OM. Flavonoids from Red Onion (Allium cepa). Phytochemistry 47 (2); 281-285. 1998Kumari K, Augusti KT, Antidiabetic effects of S-methylcystein sulphoxide on alloxan diabetes. In: PM 61(1):72-74. 1995.Kupidlowska E, Bieniak B, Ruchirawat A, Zobel AM. Influence of methyl derivatives of coumarin on mitotic activity and ultrastructure of meristemic cells of Allium cepa root tips. Phytomedicine 2 (3); 275-281. 1996Lancaster JE, Shaw ML. Gamma-Glutamyl Peptides in the Biosynthesis of S-Alk(en)yl-L-Cysteine Sulphoxides (Flavour Precursors) in Allium. Phytochemistry 28; 455-460. 1989Paradiz J. Assessement of damage to irridated onion (Allium cepa L.) by cytogenic analyses. Acta Pharm. 48; 167-178. 1998Sendl A, Elbl G, Steinke B, Redl K, Breu W, Wagner H. Comparative Pharmacological Investigations of Allium ursinum and Allium sativum. Planta Med. 58; 1-7. 1992Tverskoy L, Dmetriev A, Kozlovsky A, Grodzinsky D, Two phytoalexins from Allium-cepa bulbs. In: PH 30:799. 1991.Wagner H, Bayer Th, Dorsch W, Das antiasthmatische Wirkprinzip der Zwiebel (Allium cepa L.). In: ZPT 9(6):165. 1988.

This information is an educational aid only. It is not intended as medical advice for individual conditions or treatments.
Talk to your doctor, nurse, or pharmacist before following any medical regimen to see if it is safe and effective for you. Please read this important disclaimer about the information within our guide.

Coenzyme Q1-

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